Ceria nanoparticles that can protect against ischemic stroke.

نویسندگان

  • Chi Kyung Kim
  • Taeho Kim
  • In-Young Choi
  • Min Soh
  • Dohoung Kim
  • Young-Ju Kim
  • Hyunduk Jang
  • Hye-Sung Yang
  • Jun Yup Kim
  • Hong-Kyun Park
  • Seung Pyo Park
  • Sangseung Park
  • Taekyung Yu
  • Byung-Woo Yoon
  • Seung-Hoon Lee
  • Taeghwan Hyeon
چکیده

Uniform 3 nm-sized ceria nanoparticles can protect against ischemic stroke by scavenging reactive oxygen species (ROS) and reducing apoptosis. PEGylated ceria nanoparticles showed protective effects against ROS-induced cell death in vitro. Optimal doses of ceria nanoparticles reduced infarct volumes and the rate of ischemic cell death in vivo.

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عنوان ژورنال:
  • Angewandte Chemie

دوره 51 44  شماره 

صفحات  -

تاریخ انتشار 2012